Best Telemedicine for Semaglutide (2026)

Our expert picks for the best telemedicine providers for semaglutide treatment. Compare options for both compounded and brand-name semaglutide including Wegovy and Ozempic.

Updated: December 21, 2025 | By MatchGLP1 Editorial Team

How We Ranked

We evaluated telemedicine providers offering semaglutide based on medication options (brand vs compounded, injectable vs oral), pricing, quality certifications, customer experience, and ongoing support.

Provider Rankings

#1 Winner
Our Top Pick

Ro

Best Overall for Semaglutide

From $99/mo
4.3

Why #1?

Ro offers the complete semaglutide package - compounded starting at $99/month, brand-name Wegovy via NovoCare at $499/month, plus integrated coaching. Their LegitScript certification and established reputation make them our top semaglutide pick.

Pros

  • + Established, trusted telehealth brand
  • + LegitScript certified
  • + FDA-approved medications available
  • + Integrated coaching and lifestyle support

Cons

  • - Premium pricing compared to compounding-only providers
  • - No insurance accepted
  • - Limited to injectable medications
#2 Runner-up

Hims & Hers

Best for Oral Semaglutide

From $69/mo
4.0

Why #2?

Hims uniquely offers oral semaglutide starting at $69/month alongside injectable options. Perfect for patients who prefer pills over injections, with the flexibility to switch formats as needed.

Pros

  • + Both injectable and oral options available
  • + Direct partnership with Novo Nordisk
  • + Quick customer service response
  • + Competitive pricing for compounded medications

Cons

  • - No insurance accepted
  • - Best pricing requires upfront payment for multi-month plans
  • - Limited coaching compared to some competitors
#3 Third Place

FuturHealth

Best Quality Certification

Why #3?

FuturHealth's Valisure certification ensures compounded semaglutide quality. Their clinical outcomes data showing 58.5% better results with their program adds confidence for patients prioritizing verified quality.

Pros

  • + Large provider network (6,000+ providers)
  • + Over 1.5 million patients served
  • + Pill form available
  • + Valisure certified

Cons

  • - Compounded medications not FDA-approved
  • - Not available in all states (48 states)
  • - Cash-pay only
  • - Pricing not published
#4 Fourth

Calibrate

Best for Brand-Name Only

From $199/mo
3.8

Why #4?

Calibrate focuses exclusively on FDA-approved semaglutide (Wegovy/Ozempic) with comprehensive coaching support. Ideal for patients who want brand-name medications with a structured behavior change program.

Pros

  • + Comprehensive year-long program
  • + Focus on long-term behavior change
  • + Bi-weekly coaching sessions
  • + FDA-approved medications only

Cons

  • - Higher total cost (~$1,600+/year for program alone)
  • - Medication costs separate
  • - Slower onboarding process
  • - Requires significant time commitment
#5 Fifth

Henry Meds

Best Budget Option

From $249/mo
3.8

Why #5?

Henry Meds offers affordable compounded semaglutide with flexible month-to-month plans. Their oral option at $249/month provides a non-injection alternative at a competitive price point.

Pros

  • + Oral semaglutide option for injection-averse patients
  • + Month-to-month flexibility
  • + Transparent pricing
  • + Multiple medication options

Cons

  • - Only compounded medications (no FDA-approved brands)
  • - Prices may increase with dose escalation
  • - Reports of delayed customer support
  • - Not available in all states

About Semaglutide

Semaglutide is a GLP-1 receptor agonist that helps with weight loss and blood sugar control. It’s available as:

  • Wegovy - FDA-approved for weight management
  • Ozempic - FDA-approved for type 2 diabetes
  • Compounded semaglutide - Available during FDA shortage periods

Semaglutide Pricing Comparison

ProviderCompoundedBrand-NameOral Option
Ro$99-145/mo$499/mo (Wegovy)No
Hims$199-299/moAvailable$69/mo
FuturHealthContactAvailableYes
CalibrateN/AInsurance-basedNo
Henry Meds$297/moNo$249/mo

Injectable vs Oral Semaglutide

Injectable semaglutide is the traditional format, given as a weekly subcutaneous injection. It’s the most studied form with extensive clinical trial data.

Oral semaglutide is a newer option offered by some compounding providers. While convenient for injection-averse patients, it may have different absorption characteristics.

FAQs About Semaglutide

What’s the difference between Wegovy and Ozempic?

Both contain semaglutide. Wegovy is FDA-approved for weight loss at doses up to 2.4mg weekly. Ozempic is approved for type 2 diabetes at doses up to 2mg weekly.

How quickly does semaglutide work?

Most patients notice appetite reduction within the first few weeks. Significant weight loss typically occurs over 3-6 months with proper dose titration.

What are common side effects?

Nausea, vomiting, and constipation are common, especially during dose escalation. Most side effects improve over time as your body adjusts.

Our Methodology

Our semaglutide-specific ranking considers:

  1. Medication Options (25%): Availability of both brand (Wegovy/Ozempic) and compounded, injectable and oral formats.

  2. Pricing (25%): Competitive rates across dosage levels with transparent pricing for the full treatment journey.

  3. Quality (20%): Pharmacy certifications, manufacturer partnerships, and medication quality assurance.

  4. Support (15%): Coaching, physician access, titration guidance, and side effect management.

  5. Flexibility (15%): Month-to-month options, ability to switch formats, and cancellation policies.

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