Amazon Pharmacy vs Sesame Care

Detailed side-by-side comparison of Amazon Pharmacy and Sesame Care.

Comparing:Amazon PharmacySesame Care

Comparing 2 Providers

UPDATED
Hybrid

Amazon Pharmacy

GLP-1s, delivered.

Pricing
$149/mo

Oral GLP-1s from $149/mo cash or $25/mo with insurance; injections from $299/mo cash

Medications
Brand Name
  • Semaglutide(Wegovy, Wegovy Pill, Ozempic)
  • Tirzepatide(Zepbound)
  • Orforglipron(Foundayo)
Features
CoachingInsurance
Ratings
3.8Trustpilot
A+BBB
Pros
  • +Fully integrated care — One Medical visits, Rx management, and Amazon Pharmacy fulfillment in one experience
  • +Transparent cash-vs-insurance pricing shown side-by-side at checkout
  • +Manufacturer coupons and savings cards auto-applied to eligible orders
Cons
  • One Medical membership ($9/mo or $99/yr) required for the integrated care program (separate from Prime)
  • No compounded options — FDA-approved medications only
  • In-person visits limited to cities with One Medical clinics (virtual available everywhere)
UPDATED
Telemedicine

Sesame Care

Healthcare on your terms

Pricing
$99/mo

Success by Sesame subscription fee

Medications
Brand NameCompounded
  • Semaglutide(Wegovy, Ozempic)
  • Semaglutide Oral(Rybelsus)
  • Compounded Semaglutide
  • Tirzepatide(Zepbound, Mounjaro)
Features
No additional features listed
Ratings
4.2Trustpilot
Pros
  • +Broadest medication selection (14 options)
  • +Choice of provider
  • +Both brand and compounded options
Cons
  • Subscription fee plus medication costs
  • Brand-name medications expensive without insurance
  • No coaching or lifestyle support

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