How GLP-1 Medications Work
Understand the science behind GLP-1 receptor agonists and how they help with weight management.
GLP-1 (glucagon-like peptide-1) medications have become increasingly popular for weight management and diabetes treatment. This guide explains how these medications work in your body.
What is GLP-1?
GLP-1 is a naturally occurring hormone in your body that’s released by your intestines after eating. It plays several important roles:
- Regulates blood sugar levels
- Reduces appetite
- Slows digestion
- Signals fullness to your brain
How GLP-1 Medications Work
GLP-1 receptor agonists are synthetic versions of the natural GLP-1 hormone. They work by:
1. Blood Sugar Regulation
These medications stimulate insulin production when blood sugar levels are high, helping to maintain healthy glucose levels.
2. Appetite Suppression
By acting on receptors in the brain, GLP-1 medications reduce hunger and increase feelings of fullness.
3. Delayed Gastric Emptying
Food stays in your stomach longer, contributing to prolonged satiety and reduced calorie intake.
Types of GLP-1 Medications
- Semaglutide (Ozempic, Wegovy)
- Tirzepatide (Mounjaro, Zepbound)
- Liraglutide (Saxenda, Victoza)
- Dulaglutide (Trulicity)
Who Should Consider GLP-1 Medications?
GLP-1 medications may be appropriate for:
- Adults with type 2 diabetes
- Individuals with obesity (BMI ≥ 30)
- Those with overweight (BMI ≥ 27) and weight-related health conditions
Always consult with a healthcare provider to determine if GLP-1 medications are right for you.